As one of the souls that primarly work on original guns then..
The Colts in general have jumped. Not a 100.. try 500 to a 1000. Then again, the really nice guns have always been expensive.
On the Colts more specific then.
They´re due material choice often more run down than many of the others. Often worn to a different level. End shake of cylinder is more often than not to the point where the gun shouldn´t be used any more before major surgery.
Timing wise, off and on i´d say. A crap game just about.
However. As long as we´re talking barrel and cylinder it can be corrected. Yes, that and of course the brass parts. Frame injury though, like cracks or whatever.. walk away.
Ask to have the gun apart. It´s just getting the wedge out and removing the barrel. Hold the barrel up vs a light source and check the rifling. In essence and old Army or 51/61 Navy if present at all that is a good thing.